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Eur. Phys. J. B 12, 607-611 (1999)

Protein folding simulations in a deformed energy landscape

U.H.E. Hansmann

Department of Physics Michigan Technological University Houghton, MI 49931-1295, USA


(Received 2 September 1999)

Abstract
A modified version of stochastic tunneling, a recently introduced global optimization technique, is introduced as a new generalized-ensemble technique and tested for a benchmark peptide, Met-enkephalin. It is demonstrated that the new technique allows to evaluate folding properties and especially the glass temperature $T_{\rm g}$ of this peptide.

PACS
05.10.-a - Computational methods in statistical physics and nonlinear dynamics.
87.16.Ac - Theory and modeling; computer simulation.

© EDP Sciences, Società Italiana di Fisica, Springer-Verlag 1999