This is the first free article in the new ‘Key summaries’ series from 4open. The article offers an easy to understand version of “Visual gene network analysis of aging-specific gene co-expression in human indicates overlaps with immuno-pathological regulations” by Bibhu Parida et al., published in 4open in 2018, which examines the complex process of aging to identify a set of candidate genes that are involved in organism aging processes, using a microarray meta-analysis approach.

The ‘Key summaries’ article uses non-technical language and provides definitions to help non-experts understand, in this instance, “What happens to our bodies as we age, and why?”.

Using publicly available datasets, researchers have found that genes involved in infections and inflammatory responses are highly expressed with age, suggesting links between infection/inflammation and the ageing process."

Read the ‘Key summaries’ article - “Researchers use open-access genetic data to reveal a unique picture of ageing”

Read the original article - “Visual gene network analysis of aging-specific gene co-expression in human indicates overlaps with immuno-pathological regulations”